Copper Complexes for the Diagnostic Imaging of Alzheimer's Disease

Rhenium and technetium complexes that bind to amyloid-β plaques

DJ Hayne, AJ North, M Fodero-Tavoletti, JM White, LW Hung, A Rigopoulos, CA Mclean, PA Adlard, U Ackermann, H Tochon-Danguy, VL Villemagne, KJ Barnham, PS Donnelly

2015-03-21

Alzheimer's disease is associated with the presence of insoluble protein deposits in the brain called amyloid plaques. The major c..

Neuroprotective copper bis(thiosemicarbazonato) complexes promote neurite elongation

L Bica, JR Liddell, PS Donnelly, C Duncan, A Caragounis, I Volitakis, BM Paterson, R Cappai, A Grubman, J Camakaris, PJ Crouch, AR White

2014-02-28

Abnormal biometal homeostasis is a central feature of many neurodegenerative disorders including Alzheimer's disease (AD), Parkins..

Deregulation of subcellular biometal homeostasis through loss of the metal transporter, Zip7, in a childhood neurodegenerative disorder

A Grubman, GE Lidgerwood, C Duncan, L Bica, JL Tan, SJ Parker, A Caragounis, J Meyerowitz, I Volitakis, D Moujalled, JR Liddell, JL Hickey, M Horne, S Longmuir, J Koistinaho, PS Donnelly, PJ Crouch, I Tammen, AR White, KM Kanninen

2014-01-27

Background: Aberrant biometal metabolism is a key feature of neurodegenerative disorders including Alzheimer's and Parkinson's dis..

Metal complexes designed to bind to amyloid-β for the diagnosis and treatment of Alzheimer's disease

DJ Hayne, S Lim, PS Donnelly

2014-01-01

Alzheimer's disease is the most common form of age-related neurodegenerative dementia. The disease is characterised by the presenc..

Rhenium and technetium tricarbonyl complexes of 1,4-substituted pyridyl-1,2,3-triazole bidentate ‘click’ ligands conjugated to a targeting RGD peptide

TU Connell, DJ Hayne, Uwe Ackermann, JM White, PS Donnelly, Henri Tochon-Danguy

2014-01-01

New 1,4‐substituted pyridyl‐1,2,3‐triazole ligands with pendent phenyl isothiocyanate functional groups linked to the heterocycle ..